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Image Search Results
Journal: The AAPS Journal
Article Title: Development of a Generic Anti-PEG Antibody Assay Using BioScale’s Acoustic Membrane MicroParticle Technology
doi: 10.1208/s12248-015-9799-4
Figure Lengend Snippet: AMMP assay format: anti-PEG detection with biotin-PEG 20 kDa immobilized on the magnetic bead and detection of complex on the cartridge coated with Protein A. Biotin-PEG is coupled onto streptavidin-coated paramagnetic beads. Anti-PEG in the human serum forms complexes on the coated beads under homogeneous conditions. When samples flow across the sensor cartridge, the bead complex is captured by Protein A bound to the sensor surface, a piezoelectric membrane. This change in mass on the sensor generates a signal proportional to the mass of bound anti-PEG
Article Snippet: AMMP Type I Labeling Kit for Assay Discovery, AMMP Type II Labeling Kit for Assay Discovery, and
Techniques: